Yanai-Berar N, Ben-Itzhak O, Gree J, Nakhoul F
Department of Nephrology, Rambam Medical Center, Haifa, Israel.
Clin Nephrol. 2002 Sep;58(3):220-3. doi: 10.5414/cnp58220.
Influenza vaccination is a widely accepted practice, particularly among the elderly and high-risk individuals. Minor and transitory side effects following the vaccination are common, while systemic complications are infrequently reported. We describe here a case of a patient who presented to the emergency room with arthralgia, myalgias and purpura, following influenza vaccination. Necrotizing vasculitis associated with pauci-immune glomerulonephritis was observed on kidney biopsy. With increasing use of influenza vaccination, attention should be drawn to the possible expression of systemic adverse effects such as vasculitis and glomerulonephritis.
流感疫苗接种是一种被广泛接受的做法，尤其是在老年人和高危人群中。接种疫苗后出现轻微和短暂的副作用很常见，而全身性并发症的报告则很少。我们在此描述一例患者，该患者在接种流感疫苗后因关节痛、肌痛和紫癜就诊于急诊室。肾活检发现与寡免疫性肾小球肾炎相关的坏死性血管炎。随着流感疫苗接种的使用增加，应注意可能出现的全身性不良反应，如血管炎和肾小球肾炎。
