Tavadia S, Drummond A, Evans C D, Wainwright N J
Department of Dermatology, Western Infirmary, Glasgow, UK.
Clin Exp Dermatol. 2003 Mar;28(2):154-6. doi: 10.1046/j.1365-2230.2003.01188.x.
Influenza vaccination is recommended for all people over 75 years of age and for an expanding range of other indications. Side-effects of influenza vaccination are usually mild but we describe four cases of leucocytoclastic vasculitis following influenza vaccination. The four patients, who were all elderly, presented with cutaneous vasculitis but all had abnormal urinalysis suggestive of associated renal involvement. Since 1974 only 10 cases of vasculitis following influenza vaccination have been reported in the literature. The clinical features of these cases are reviewed. As the use of influenza vaccination is likely to increase, dermatologists should be aware of the possible association with vasculitis.
建议所有75岁以上人群以及其他适用范围不断扩大的人群接种流感疫苗。流感疫苗的副作用通常较为轻微，但我们描述了4例接种流感疫苗后发生白细胞破碎性血管炎的病例。这4例患者均为老年人，表现为皮肤血管炎，但尿液分析均异常，提示存在相关肾脏受累。自1974年以来，文献中仅报道了10例接种流感疫苗后发生血管炎的病例。本文对这些病例的临床特征进行了综述。鉴于流感疫苗的使用可能会增加，皮肤科医生应意识到其与血管炎之间可能存在的关联。
