Knoll W, Stark G
J Membr Biol. 1975;25(3-4):249-70. doi: 10.1007/BF01868578.
The time course of the current following a voltage jump, which is applied to monoglyceride bilayers in the presence of valinomycin, shows two relaxation times. This is basically in agreement with a simple carrier model which has been described in full detail formerly. Relaxation times and amplitudes allow a calculation of the rate constants of the transport model. The presented data supplement an analysis which was hitherto based only on the slower relaxation process and on information derived from the nonlinearity of current-voltage characteristics. The additional resolution of the faster relaxation time allowed an approximate determination of the voltage dependence of the translocation rate constant for carrier-ion-complex and provided evidence for a small voltage dependence of the interfacial reaction. The dependence of the relaxation parameters on the ion concentration in the aqueous phase was interpreted assuming a saturation of the ion concentration at the reaction plane at high bulk concentrations.
在缬氨霉素存在的情况下，对甘油单酯双层施加电压阶跃后电流随时间的变化过程显示出两个弛豫时间。这基本上与之前已详细描述的简单载体模型一致。弛豫时间和幅度使得能够计算传输模型的速率常数。所呈现的数据补充了一种分析，该分析迄今为止仅基于较慢的弛豫过程以及从电流 - 电压特性的非线性得出的信息。更快弛豫时间的额外分辨率使得能够近似确定载体 - 离子复合物转运速率常数的电压依赖性，并为界面反应的小电压依赖性提供了证据。假设在高本体浓度下反应平面处离子浓度饱和，对弛豫参数对水相离子浓度的依赖性进行了解释。
