Hansen Eva S
Department of Occupational and Environmental Health, Institute of Public Health, University of Copenhagen, Denmark.
Int J Occup Environ Health. 2002 Jul-Sep;8(3):281-3. doi: 10.1179/107735202800338867.
The author considers the validity of a recent study of lung cancer among European rock and slag wool workers. The study failed to demonstrate an association between lung cancer and exposure to man-made vitreous fibers and also did not manage to demonstrate a relationship between lung cancer and asbestos exposure, an odd finding that casts doubt on its validity. This article deals with bias towards the null and other aspects of the reviewed study that may explain its failure to demonstrate an effect of asbestos, concluding that the study does not add to knowledge about a possible carcinogenic effect of rock and slag wool fibers, the apparent null results simply being non-informative because of the study's poor ability to detect existing associations.
作者对近期一项关于欧洲岩棉和矿渣棉工人肺癌的研究的有效性进行了考量。该研究未能证明肺癌与接触人造玻璃纤维之间存在关联，且也未能证明肺癌与石棉接触之间存在关系，这一奇怪的发现令人对其有效性产生质疑。本文探讨了该综述研究中对零假设的偏向以及其他可能解释其未能证明石棉效应的方面，得出的结论是，该研究并未增加对岩棉和矿渣棉纤维可能致癌作用的认识，由于该研究检测现有关联的能力较差，其明显的零结果实际上并无信息价值。
