Koloski Natasha A, Talley Nicholas J, Boyce Philip M
Department of Medicine, University of Sydney, Nepean Hospital, Penrith, New South Wales, Australia.
Am J Gastroenterol. 2002 Sep;97(9):2290-9. doi: 10.1111/j.1572-0241.2002.05783.x.
Functional GI disorders (FGIDs) are common in clinical practice, but little is known about the epidemiology of these disorders in the general population. We aimed to determine the prevalence, association with psychological morbidity, and health care seeking behavior of FGIDs in the population.
A random sample of subjects (n = 4500) aged > or = 18 yr and representative of the Australian population were mailed a validated questionnaire. For these subjects we measured all Rome I GI symptoms and physician visits over the past 12 months, as well as neuroticism, anxiety, depression, and somatic distress.
The response rate for the study was 72%. The prevalence of any FGID was 34.6%, and 62.1% of these subjects had consulted a physician. There was considerable overlap of the FGIDs (19.2% had more than two disorders). Independent predictors for an FGID diagnosis were neuroticism, somatic distress, anxiety, bowel habit disturbance, abdominal pain frequency, and increasing age. However, psychological morbidity did not independently discriminate between consulters and nonconsulters with an FGID.
More than one third of the general population have one or more FGIDs. There seems to be a modest link between psychological morbidity and FGIDs, although other unknown factors seem to be more important in explaining health care seeking for these disorders.
功能性胃肠疾病（FGIDs）在临床实践中很常见，但对于这些疾病在普通人群中的流行病学情况知之甚少。我们旨在确定FGIDs在人群中的患病率、与心理疾病的关联以及寻求医疗保健的行为。
向年龄大于或等于18岁且具有澳大利亚人群代表性的4500名受试者随机抽样邮寄一份经过验证的问卷。对于这些受试者，我们测量了过去12个月内所有罗马I型胃肠症状和就医情况，以及神经质、焦虑、抑郁和躯体困扰。
该研究的应答率为72%。任何FGID的患病率为34.6%，其中62.1%的受试者咨询过医生。FGIDs之间存在相当大的重叠（19.2%的受试者患有两种以上疾病）。FGID诊断的独立预测因素为神经质、躯体困扰、焦虑、排便习惯紊乱、腹痛频率和年龄增长。然而，心理疾病并不能独立区分FGID的就医者和未就医者。
超过三分之一的普通人群患有一种或多种FGIDs。心理疾病与FGIDs之间似乎存在适度的联系，尽管其他未知因素在解释这些疾病的就医行为方面似乎更为重要。
