Simbirtsev A S, Konusova V G, McHedlidze G Sh, Fidarov E Z, Paramonov B A, Chebotarev V Yu
Institute of High-Purity Biological Preparations; St. Petersburg-Technology, St. Petersburg.
Bull Exp Biol Med. 2002 Mar;133(3):265-7. doi: 10.1023/a:1015842918995.
We studied the effects of pine resin and Biopin ointment used for the therapy of burns, wounds, purulent and inflammatory diseases on the content of lipid peroxidation products, including primary (conjugated dienes), secondary (malonic dialdehyde and ketodienes), and end products (Schiff bases), and content of isolated double bonds in the spleen and liver. Repeated application of Biopin did not modulate lipid peroxidation. The inhibitory effect of this preparation was observed only in the initial short period after application.
我们研究了用于治疗烧伤、伤口、化脓性和炎症性疾病的松脂和比奥平软膏对脂质过氧化产物含量的影响,这些产物包括初级产物(共轭二烯)、次级产物(丙二醛和酮二烯)以及终产物(席夫碱),同时还研究了其对脾脏和肝脏中孤立双键含量的影响。重复使用比奥平并未调节脂质过氧化。仅在用药后的最初短时间内观察到该制剂具有抑制作用。