Simbirtsev A S, Konusova V G, Mchedlidze G Sh, Fidarov E Z, Paramonov B A, Chebotarev V Yu
Institute of High-Purity Biological Preparations, St. Petersburg.
Bull Exp Biol Med. 2002 Apr;133(4):384-5. doi: 10.1023/a:1016258323713.
We studied properties of ointment Biopin containing pine resin and used for the therapy of burns, wounds, and purulent and inflammatory diseases. Long-term treatment with this preparation in clinical doses had no effect on the nonspecific, but modulated the specific immune response. Biopin ointment inhibited humoral, but stimulated cell immunity. Neither local irritation, nor allergic reactions were found after long-term epicutaneous application of the preparation.
我们研究了含有松脂的Biopin软膏的特性，该软膏用于治疗烧伤、伤口以及化脓性和炎性疾病。以临床剂量长期使用该制剂对非特异性免疫无影响，但可调节特异性免疫反应。Biopin软膏抑制体液免疫，但刺激细胞免疫。长期经皮应用该制剂后，未发现局部刺激或过敏反应。
