Cervantes L F, Haua Kuri J, Castillo A, Guzmán C
Rev Gastroenterol Mex. 1975 Jul-Aug;40(4):185-93.
The patients reviewed in this study are thirty individuals with acute amoebic hepatic abscess. They were given tinidazol, two grams a day in one dose, for three days, with the object of ascertaining if this would be adequate treatment and without important side effects. The clinical diagnosis was confirmed by X-rays of the thoraz and abdomen, laboratory studies and liver scans. This latter as well as the laboratory tests were repeated at 10 and 20 days. Several of the patients were considered to be gravely ill. In 43% of the patients there was hepatomegaly grade II or II, in 30% there was jaundice, in 64% the abscess was very large and in 30% there were several abscesses. In keeping with the guide lines previously agreed on, 28 patients were cured, or that is 93%. There were no important side effects.
本研究回顾的患者为30例急性阿米巴肝脓肿患者。给予替硝唑,每日2克,单次服用,共3天,目的是确定这是否为充分的治疗方法且无严重副作用。临床诊断通过胸部和腹部X线检查、实验室研究及肝脏扫描得以证实。肝脏扫描及实验室检查在第10天和第20天重复进行。部分患者病情严重。43%的患者有II级或III级肝肿大,30%的患者有黄疸,64%的患者脓肿非常大,30%的患者有多个脓肿。按照先前商定的指导方针,28例患者治愈,即93%。无严重副作用。