Kornfeld P, Mittag T N, Genkins G, Horowitz S, Papatestas A E
Neurology. 1975 Oct;25(10):998-9. doi: 10.1212/wnl.25.10.998.
Pyridostigmine-carbon 14 (P-C14) excretion studies in myasthenia gravis patients who had had thymectomies failed to produce any significant difference from results observed in myasthenic patients who had not had thymectomies. Thus, change in P-C14 metabolism cannot help explain decreased anticholinesterase requirements and electromyographic changes observed in some patients following thymectomy.
对已接受胸腺切除术的重症肌无力患者进行的吡啶斯的明 - 碳14(P - C14)排泄研究,结果与未接受胸腺切除术的重症肌无力患者相比,未产生任何显著差异。因此,P - C14代谢的变化无法解释部分患者胸腺切除术后抗胆碱酯酶需求的降低以及肌电图变化。