Ruiz-Vega G, Pérez-Ordaz L, León-Huéramo O, Cruz-Vázquez E, Sánchez-Diaz N
Instituto de Física y Matemáticas, Universidad Michoacana, Morelia, Michoacán, Mexico.
Homeopathy. 2002 Apr;91(2):80-4. doi: 10.1054/homp.2002.0005.
The effects of Coffea cruda 30 and 200c and caffeine on the sleep pattern of rats were investigated. Treatments were administered orally at the beginning of the sleeping period. EEG from the parietal region was recorded. Delta (0.5-2.5 Hz) and slow (< 1 Hz) waves are two of the major oscillation types that characterize neocortical electrical activity. The spectral power in these bands and the power ratio between 0.32-0.48 Hz and the delta band (slow/delta power ratio) for control and treatment groups were analyzed blind. Power in the delta band was significantly higher than baseline for Coffea 30c and caffeine (15.5mg/kg). An increase in the slow/delta power ratio between control and treatment was detected for Coffea cruda 30 and 200c. Coffea 30c and caffeine have similar effects on sleep pattern, enhancing delta power; Coffea cruda 200c appears to affect only the synchronization.
研究了30C和200C的生咖啡以及咖啡因对大鼠睡眠模式的影响。在睡眠期开始时口服给药。记录顶叶区域的脑电图。δ波（0.5-2.5赫兹）和慢波（<1赫兹）是表征新皮质电活动的两种主要振荡类型。对对照组和治疗组的这些频段的频谱功率以及0.32-0.48赫兹与δ频段之间的功率比（慢波/δ波功率比）进行了盲法分析。对于30C的生咖啡和咖啡因（15.5毫克/千克），δ频段的功率显著高于基线。检测到30C和200C的生咖啡在对照组和治疗组之间的慢波/δ波功率比有所增加。30C的生咖啡和咖啡因对睡眠模式有相似的影响，增强了δ波功率；200C的生咖啡似乎仅影响同步性。
