切尔诺贝利事故清理人员中的甲状腺癌发病率。辐射风险与外部辐射剂量无关。

Thyroid cancer incidence among liquidators of the Chernobyl accident. Absence of dependence of radiation risks on external radiation dose.

作者信息

Ivanov V K, Tsyb A F, Petrov A V, Maksioutov M A, Shilyaeva T P, Kochergina E V

机构信息

4 Korolyov street, Obninsk, Kaluga region, 249020 Russia.

出版信息

Radiat Environ Biophys. 2002 Sep;41(3):195-8. doi: 10.1007/s00411-002-0163-6. Epub 2002 Aug 28.

DOI:10.1007/s00411-002-0163-6

PMID:12373328

Abstract

The increase of thyroid cancer incidence rate among children living in the Chernobyl contaminated territories of Belarus, Russia and Ukraine has widely been accepted. Our current work deals with thyroid cancer incidence in the cohort of liquidators (99024 persons) living in 6 regions of Russia: North-West, Volgo-Vyatsky, Central-Chernozemny, Povolzhsky, North-Caucasus and Urals. In the period 1986-1998, a total of 58 thyroid cancer cases were detected in this cohort. We found a statistically significant increase of the thyroid cancer incidence rate in liquidators as compared to the baseline (male population of Russia) level (SIR=4.33, 95% CI: 3.29; 5.60). It was demonstrated that there is no dependence of incidence rates due to external radiation exposure (ERR/Gy=-2.23, 95% CI: -4.67; 0.22).

摘要

居住在白俄罗斯、俄罗斯和乌克兰受切尔诺贝利污染地区的儿童甲状腺癌发病率上升已被广泛认可。我们目前的工作涉及生活在俄罗斯6个地区的清理人员（99024人）队列中的甲状腺癌发病率：西北、伏尔加-维亚茨基、中央黑土、伏尔加河沿岸、北高加索和乌拉尔。在1986年至1998年期间，该队列中总共检测出58例甲状腺癌病例。我们发现，与基线水平（俄罗斯男性人口）相比，清理人员的甲状腺癌发病率有统计学上的显著增加（标准化发病比=4.33，95%置信区间：3.29；5.60）。结果表明，外部辐射暴露导致的发病率不存在依赖性（每西弗特超额相对危险度=-2.23，95%置信区间：-4.67；0.22）。