Takeda Hiroaki, Ling Motofumi, Ochi Masaru, Watanabe Keitarou
Department of Internal Medicine, Saiseikai Yamagata Saisei Hospital, 79-1 Okimachi, Yamagata 990-8545, Japan.
J Infect Chemother. 2002 Sep;8(3):262-5. doi: 10.1007/s10156-002-0180-z.
Adult Still's disease is an important differential diagnosis of pyretic disease and it does not necessarily appear to be a distinct disease entity. The etiology of adult Still's disease is not yet known. However, it has been considered that adult Still's disease may be triggered by certain infections, such as the Coxsackie, parvo B19, rubella, mumps, Epstein-Barr, and cytomegalo virus, as well as mycoplasma, toxoplasma, and so on. Recently, we experienced a patient with adult Still's disease with an increased Chlamydia pneumoniae antibody titer. The titer decreased slowly after the beginning of steroid therapy, associated with improvement of clinical symptoms. In this report we mention the relationship between the pathogenesis of adult Still's disease and a high titer of Chlamydia pneumoniae antibody.
成人斯蒂尔病是发热性疾病的重要鉴别诊断,它不一定表现为一种独特的疾病实体。成人斯蒂尔病的病因尚不清楚。然而,有人认为成人斯蒂尔病可能由某些感染引发,如柯萨奇病毒、细小病毒B19、风疹、腮腺炎、EB病毒和巨细胞病毒,以及支原体、弓形虫等。最近,我们遇到一名成人斯蒂尔病患者,其肺炎衣原体抗体滴度升高。开始使用类固醇治疗后,滴度缓慢下降,同时临床症状有所改善。在本报告中,我们提及成人斯蒂尔病的发病机制与高滴度肺炎衣原体抗体之间的关系。