• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

特发性生长激素缺乏症患儿的低血红蛋白水平

Low hemoglobin levels in children with in idiopathic growth hormone deficiency.

作者信息

Eugster Erica A, Fisch Mark, Walvoord Emily C, DiMeglio Linda A, Pescovitz Ora H

机构信息

Department of Pediatrics, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202, USA.

出版信息

Endocrine. 2002 Jul;18(2):135-6. doi: 10.1385/ENDO:18:2:135.

DOI:10.1385/ENDO:18:2:135
PMID:12374460
Abstract

Multiple lines of evidence have implicated the growth hormone (GH) axis in the regulation of erythropoiesis. To test the hypothesis that GH deficiency is associated with hematologic abnormalities, we analyzed pretreatment hemoglobin levels in 100 children with GH deficiency. Hemoglobin levels were decreased in children with GH deficiency compared with age-corrected norms.

摘要

多条证据表明生长激素(GH)轴参与红细胞生成的调节。为了验证生长激素缺乏与血液学异常相关的假说,我们分析了100例生长激素缺乏儿童的治疗前血红蛋白水平。与年龄校正后的正常标准相比,生长激素缺乏儿童的血红蛋白水平降低。

相似文献

1
Low hemoglobin levels in children with in idiopathic growth hormone deficiency.特发性生长激素缺乏症患儿的低血红蛋白水平
Endocrine. 2002 Jul;18(2):135-6. doi: 10.1385/ENDO:18:2:135.
2
Effect of recombinant human growth hormone (rhGH) on hemoglobin concentration in children with idiopathic growth hormone deficiency-related anemia.重组人生长激素(rhGH)对特发性生长激素缺乏相关贫血患儿血红蛋白浓度的影响。
J Pediatr Hematol Oncol. 2012 Aug;34(6):407-11. doi: 10.1097/MPH.0b013e318253f082.
3
Frequency of growth hormone deficiency in short statured children.身材矮小儿童中生长激素缺乏症的发生率。
J Coll Physicians Surg Pak. 2005 May;15(5):295-8.
4
[The effect of GH on erythropoiesis in vivo].[生长激素对体内红细胞生成的影响]
Minerva Endocrinol. 1993 Jun;18(2):83-5.
5
Estrogen priming effect on growth hormone (GH) provocative test: a useful tool for the diagnosis of GH deficiency.雌激素对生长激素(GH)激发试验的启动效应:一种诊断生长激素缺乏症的有用工具。
J Clin Endocrinol Metab. 2000 Nov;85(11):4168-72. doi: 10.1210/jcem.85.11.6928.
6
Assessing short-statured children for growth hormone deficiency.评估身材矮小儿童是否存在生长激素缺乏症。
Horm Res. 2003;60(1):34-42. doi: 10.1159/000070825.
7
[Homocysteine levels in growth hormone deficient children and adolescents before and after one year of recombinant human growth hormone (GH) replacement therapy].重组人生长激素(GH)替代治疗一年前后生长激素缺乏儿童及青少年的同型半胱氨酸水平
Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 2004;10(2):87-92.
8
Partial growth hormone deficiency (GHD) in children has more similarities to idiopathic short stature than to severe GHD.儿童部分生长激素缺乏(GHD)与特发性身材矮小的相似之处多于与严重GHD的相似之处。
Endokrynol Pol. 2007 May-Jun;58(3):182-7.
9
Insulin-like growth factor I and growth responses during the first year of growth hormone treatment in KIGS patients with idiopathic growth hormone deficiency, acquired growth hormone deficiency, turner syndrome and born small for gestational age.胰岛素样生长因子I与生长激素治疗第一年期间KIGS中特发性生长激素缺乏症、获得性生长激素缺乏症、特纳综合征和小于胎龄儿患者的生长反应。
Horm Res. 2009 Jan;71 Suppl 1:39-45. doi: 10.1159/000178036. Epub 2009 Jan 21.
10
Long-term effects of growth hormone (GH) replacement therapy on hematopoiesis in a large cohort of children with GH deficiency.生长激素(GH)替代疗法对一大群生长激素缺乏儿童造血功能的长期影响。
Endocrine. 2016 Jul;53(1):192-8. doi: 10.1007/s12020-015-0781-9. Epub 2015 Oct 28.

引用本文的文献

1
Association Between Hemoglobin and Growth Hormone Peak in Chinese Children and Adolescents with Short Stature: A Cross-Sectional Study.中国矮小儿童和青少年血红蛋白与生长激素峰值之间的关联:一项横断面研究
Int J Gen Med. 2021 Feb 16;14:497-504. doi: 10.2147/IJGM.S292920. eCollection 2021.
2
An examination of the effects of different doses of recombinant human growth hormone on children with growth hormone deficiency.不同剂量重组人生长激素对生长激素缺乏症儿童影响的研究
Exp Ther Med. 2016 May;11(5):1647-1652. doi: 10.3892/etm.2016.3091. Epub 2016 Feb 19.
3
Long-term effects of growth hormone (GH) replacement therapy on hematopoiesis in a large cohort of children with GH deficiency.

本文引用的文献

1
Development of a transgenic mouse that overexpresses a novel product of the growth hormone-releasing hormone gene.
Endocrinology. 2000 Apr;141(4):1377-83. doi: 10.1210/endo.141.4.7422.
2
Anemia in children with cartilage-hair hypoplasia is related to body growth and to the insulin-like growth factor system.软骨毛发发育不全患儿的贫血与身体生长及胰岛素样生长因子系统有关。
J Clin Endocrinol Metab. 2000 Feb;85(2):563-8. doi: 10.1210/jcem.85.2.6339.
3
The influence of growth hormone substitution therapy on erythroid and myeloid progenitor cells and on peripheral blood cells in adult patients with growth hormone deficiency.生长激素替代疗法对成年生长激素缺乏患者红系和髓系祖细胞及外周血细胞的影响。
生长激素(GH)替代疗法对一大群生长激素缺乏儿童造血功能的长期影响。
Endocrine. 2016 Jul;53(1):192-8. doi: 10.1007/s12020-015-0781-9. Epub 2015 Oct 28.
4
Effects of growth hormone therapeutic supplementation on hematopoietic stem/progenitor cells in children with growth hormone deficiency: focus on proliferation and differentiation capabilities.生长激素治疗性补充对生长激素缺乏症儿童造血干细胞/祖细胞的影响:聚焦增殖与分化能力
Endocrine. 2015 Sep;50(1):162-75. doi: 10.1007/s12020-015-0591-0. Epub 2015 Apr 29.
5
Novel serum protein biomarkers indicative of growth hormone doping in healthy human subjects.新型血清蛋白生物标志物可指示健康人体的生长激素滥用。
Proteomics. 2011 Sep;11(17):3565-71. doi: 10.1002/pmic.201100077. Epub 2011 Jul 27.
6
Growth hormone replacement therapy in growth hormone deficient children and adults: Effects on hemochrome.生长激素缺乏儿童和成人的生长激素替代疗法:对血色素的影响。
J Endocrinol Invest. 2006 May;29(5):399-404. doi: 10.1007/BF03344122.
Eur J Clin Invest. 1996 Dec;26(12):1175-81. doi: 10.1046/j.1365-2362.1996.690604.x.
4
Remission of polycythemia vera after surgical cure of acromegaly.肢端肥大症手术治愈后真性红细胞增多症的缓解
Ann Intern Med. 1996 Mar 1;124(5):495-6. doi: 10.7326/0003-4819-124-5-199603010-00006.
5
Increases in hemoglobin concentration and iron needs in response to growth hormone treatment.生长激素治疗后血红蛋白浓度升高及铁需求增加。
J Pediatr. 1994 Aug;125(2):242-5. doi: 10.1016/s0022-3476(94)70203-9.
6
Insulin-like growth factor I stimulates erythropoiesis in hypophysectomized rats.胰岛素样生长因子I刺激垂体切除大鼠的红细胞生成。
Proc Natl Acad Sci U S A. 1988 Oct;85(20):7825-9. doi: 10.1073/pnas.85.20.7825.
7
Percentile curves for hemoglobin and red cell volume in infancy and childhood.婴幼儿及儿童血红蛋白和红细胞容积百分位数曲线。
J Pediatr. 1979 Jan;94(1):26-31. doi: 10.1016/s0022-3476(79)80344-3.