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俄罗斯人群中九个Profiler Plus基因座的遗传变异。

Genetic variation of the nine Profiler Plus loci in Russians.

作者信息

Kornienko Igor V, Vodolazhsky Dmitrij I, Ivanov Pavel L

机构信息

124 Central Laboratory for Medical Forensic Identification of the Department of Defense, 60 Lermontovskaya st., 344010 Rostov-on-Don, Russia.

出版信息

Int J Legal Med. 2002 Oct;116(5):309-11. doi: 10.1007/s00414-002-0309-8. Epub 2002 Jun 8.

Abstract

This paper presents allele frequency distributions from a representative population sample of the Russian Federation for the nine loci (D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820) which constitute the commercially available Profiler Plus PCR amplification kit. DNA samples of 402 Russian individuals from 57 regions of the Russian Federation were amplified in a multiplex reaction with subsequent genotyping using an ABI Prism 377 DNA sequencer. The population data obtained for genotype and allele frequencies conformed to Hardy-Weinberg expectations (HWE).

摘要

本文展示了来自俄罗斯联邦代表性人群样本的九个基因座(D3S1358、vWA、FGA、D8S1179、D21S11、D18S51、D5S818、D13S317和D7S820)的等位基因频率分布情况,这些基因座构成了市售的Profiler Plus PCR扩增试剂盒。对来自俄罗斯联邦57个地区的402名俄罗斯个体的DNA样本进行多重反应扩增,随后使用ABI Prism 377 DNA测序仪进行基因分型。获得的基因型和等位基因频率的群体数据符合哈迪-温伯格平衡预期(HWE)。

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