南山藤花中的多氧孕甾烷糖苷。

Polyoxypregnane glycosides from the flowers of Dregea volubilis.

作者信息

Sahu Niranjan, Panda Nilendu, Mandal Nirup, Banerjee Sukdeb, Koike Kazuo, Nikaido Tamotsu

机构信息

Indian Institute of Chemical Biology, 4 Raja SC Mullick Road, Jadavpur, -700032, Kolkata, India.

出版信息

Phytochemistry. 2002 Oct;61(4):383-8. doi: 10.1016/s0031-9422(02)00260-1.

DOI:10.1016/s0031-9422(02)00260-1

PMID:12377230

Abstract

Three novel polyoxypregnane glycosides, volubiloside A, B and C (1-3), were isolated from the flowers of Dregea volubilis Linn., and their structures were elucidated as drevogenin D-3-O-beta-D-glucopyranosyl (1-->4)-6-deoxy-3-O-methyl-beta-D-allopyranosyl (1-->4)-beta-D-cymaropyranosyl (1-->4)-beta-D-cymaropyranoside, drevogenin D-3-O-beta-D-glucopyranosyl (1-->4)-6-deoxy-3-O-methyl-beta-D-allopyranosyl (1-->4)-beta-D-cymaropyranosyl (1-->4)-beta-D-digitoxopyranoside and drevogenin P-3-O-beta-D-glucopyranosyl (1-->4)-6-deoxy-3-O-methyl-beta-D-allopyranosyl (1-->4)-beta-D-cymaropyranosyl (1-->4)-beta-D-cymaropyranoside, respectively, on the basis of extensive NMR experiments, MALDI-TOF MS, and some chemical strategies.

摘要

从萝藦科植物南山藤（Dregea volubilis Linn.）的花中分离出三种新型多氧孕甾烷糖苷，即volubiloside A、B和C（1 - 3），并通过广泛的核磁共振实验、基质辅助激光解吸电离飞行时间质谱（MALDI - TOF MS）和一些化学方法，分别确定它们的结构为drevogenin D - 3 - O - β - D - 吡喃葡萄糖基（1→4）- 6 - 脱氧 - 3 - O - 甲基 - β - D - 阿洛吡喃糖基（1→4）- β - D - 洋地黄毒糖基（1→4）- β - D - 洋地黄毒糖苷、drevogenin D - 3 - O - β - D - 吡喃葡萄糖基（1→4）- 6 - 脱氧 - 3 - O - 甲基 - β - D - 阿洛吡喃糖基（1→4）- β - D - 洋地黄毒糖基（1→4）- β - D - 地高辛吡喃糖苷和drevogenin P - 3 - O - β - D - 吡喃葡萄糖基（1→4）- 6 - 脱氧 - 3 - O - 甲基 - β - D - 阿洛吡喃糖基（1→4）- β - D - 洋地黄毒糖基（1→4）- β - D - 洋地黄毒糖苷。