Park Chang Kil, Choi Hwan Yeong, Oh In Young, Kim Myung Suk
Department of Anesthesiology, Eulji University School of Medicine, Daejon, Korea.
J Korean Med Sci. 2002 Oct;17(5):715-7. doi: 10.3346/jkms.2002.17.5.715.
Patient-controlled analgesia (PCA) is an important means for postoperative analgesia with parenteral opioid. However, postoperative nausea and vomiting (PONV) remains a major problem with a PCA system. Droperidol is used in PCA to prevent PONV. Extrapyramidal reactions by droperidol are, however, occasionally induced. We describe two cases of severe extrapyramidal hypertonic syndrome with an intravenous administration of droperidol in PCA in young patients, following orthopedic surgery.
患者自控镇痛（PCA）是术后胃肠外给予阿片类药物镇痛的重要手段。然而，术后恶心呕吐（PONV）仍是PCA系统的一个主要问题。氟哌利多用于PCA以预防PONV。然而，氟哌利多偶尔会引起锥体外系反应。我们描述了两例年轻患者在骨科手术后PCA静脉注射氟哌利多时发生严重锥体外系高张综合征的病例。
