Kobayashi Toshio, Madokoro Shigeki, Wada Yuji, Misaki Kiwamu, Nakagawa Hiroki
Center of Psychiatry and Neurology, Fukui Prefecture Hospital, Fukui, Japan.
Neuropsychobiology. 2002;46(2):104-10. doi: 10.1159/000065420.
Our study was designed to investigate the influence of alcohol on sleep using the correlation dimension (D2) analysis. Polysomnography (PSG) was performed in 10 adult human males during a baseline night (BL-N) and an ethanol (0.8 g/kg body weight) night (Et-N). The mean D2 values during the Et-N and BL-N decreased significantly from wakefulness to stages 1, 2, and 3+4 of nonrapid eye movement (non-REM) sleep, and increased during REM sleep. The mean D2 of the sleep electroencephalogram (EEG) during stage 2 during the Et-N was significantly higher than during BL-N. In addition, the mean D2 values of the sleep EEG for the second, third and fourth sleep cycles during the Et-N were significantly higher than during the BL-N. These significant differences between BL-N and Et-N were not recognized by spectral and visual analyses. Our results suggest that D2 is a potentially useful parameter for quantitative analysis of the effect of ethanol on sleep EEGs throughout the entire night.
我们的研究旨在通过关联维数（D2）分析来探究酒精对睡眠的影响。在10名成年男性中进行了多导睡眠图（PSG）检查，分别在基线夜（BL-N）和乙醇（0.8克/千克体重）夜（Et-N）进行。Et-N和BL-N期间，从清醒到非快速眼动（non-REM）睡眠的第1、2和3+4阶段，平均D2值显著下降，而在快速眼动睡眠期间则升高。Et-N期间第2阶段睡眠脑电图（EEG）的平均D2值显著高于BL-N期间。此外，Et-N期间第二、第三和第四个睡眠周期的睡眠EEG平均D2值显著高于BL-N期间。光谱分析和视觉分析未识别出BL-N和Et-N之间的这些显著差异。我们的结果表明，D2是定量分析乙醇对整夜睡眠EEG影响的一个潜在有用参数。
