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嗜酸性粒细胞相关的胃肠道疾病:一项基于万维网的注册研究

Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry.

作者信息

Guajardo Jesus R, Plotnick Lauren M, Fende Jennifer M, Collins Margaret H, Putnam Philip E, Rothenberg Marc E

机构信息

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

出版信息

J Pediatr. 2002 Oct;141(4):576-81. doi: 10.1067/mpd.2002.127663.

DOI:10.1067/mpd.2002.127663
PMID:12378201
Abstract

A world wide web database was established that tracked features of eosinophil-associated gastrointestinal disorders; 80% had coexisting atopic disease, 62% had food sensitization, and 16% had an immediate family member with a similar disorder. Developmental delay, seizure disorders, and congenital anomalies were seen in a proportion of respondents. The world wide web has proven to be an efficient tool to gather patient information, allowing us to define distinguishing features of various eosinophil-associated gastrointestinal disorders and to establish that these disorders have strong genetic and allergic components.

摘要

建立了一个万维网数据库,用于追踪嗜酸性粒细胞相关胃肠道疾病的特征;80%的患者同时患有特应性疾病,62%的患者有食物过敏,16%的患者有直系亲属患有类似疾病。一部分受访者出现发育迟缓、癫痫障碍和先天性异常。事实证明,万维网是收集患者信息的有效工具,使我们能够定义各种嗜酸性粒细胞相关胃肠道疾病的显著特征,并确定这些疾病具有很强的遗传和过敏成分。

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