Shabani R, Islami H, Haliti N, Qehaja N, Ahmetaj H, Jakupi M, Sopa R, Gashi-Luci L, Gashi-Naka S
Institut za patologiju, farmakologiju, klinicku fiziologiju i sudsku medicinu, UKC Medicinski fakultet Pristina.
Med Arh. 2002;56(3):127-9.
The aim of this paper was the registration of the answers of the smooth musculature of the trachea at the different concentrations of ethanol, at the gestationary weeks of the newborns with the respiratory distress syndrome. In vitro examination was worked at the nonhuman preparations of the trachea of the newborns at autopsy material, the same material of the trachea and the lungs is fixed on 10% puferized formaline for the pathomorphologic examinations (RDS). The incubation of the preparation is performed on the water bath with Kreps solution, with the constant aerozation (O2 95% and CO2 5%). The answers are registered by means of the Transducer Statham UC2 at higher canal written physiography Watanabe HSE 6600. The preparations are treated with various concentrations of ethanol 96% (0.2 ml, 0.5 ml and 1.0 ml). From the received results we came to the conclusion that the effect of ethanol in the various concentrations at the smooth musculature of the trachea in the newborns with RDS, is demonstrated the contractile or the relaxing effect without statistic significance in various gestational weeks (p > 0.05).
本文的目的是记录患有呼吸窘迫综合征的新生儿在不同孕周时，气管平滑肌对不同浓度乙醇的反应。采用新生儿尸检材料的气管非人体标本进行体外实验，将相同的气管和肺组织材料固定在10%的多聚甲醛中用于病理形态学检查（呼吸窘迫综合征）。标本在含有克雷布斯溶液的水浴中孵育，并持续通气（氧气95%，二氧化碳5%）。通过斯塔瑟姆UC2传感器在渡边HSE 6600型高级通道书写生理记录仪上记录反应。标本用不同浓度的96%乙醇（0.2毫升、0.5毫升和1.0毫升）处理。根据所得结果，我们得出结论：在患有呼吸窘迫综合征的新生儿中，不同浓度乙醇对气管平滑肌的作用，在不同孕周时表现为收缩或舒张作用，但无统计学意义（p>0.05）。
