Islami Hilmi, Shabani R, Rama Adem, Disba M, Dida B, Azizi E
Medicinski Fakultet Univerziteta u Pristini, Kosovo.
Med Arh. 2003;57(2):67-70.
It is expressed in vitro answer of the soft musculature of the tracheobronchial system of the newborns from 12 to 18 weeks of the gestation, with the hypersecretion and normosecretin of the tracheal gland. On 30 tracheal preparations taken by autopsy' of the dead children, was followed-up the answer of the tracheal soft musculature (SMT) on acetylcholine, dopamine, histamine and serotonine in the concentrations from 110(-4), 10(-3), 10(-2), 10(-1) M/L. The results illustrate that acetylcholyne, and histamine in the mentioned concentrations provoked the statistically significant answers of GMT with the hypersecretion and normosecretion of the tracheal glands (p < 0.01). On the contrary, dopamine and serotonine have not provoked statistically significant answers of these structures (p > 0.1), what illustrates that also dopaminergic and serotoninergic receptors at tracheobronchila system are not sufficient developed in this age of life. The answers of the tracheal-bronchial rings with hypersection of the tracheal glands a little more emphasized than the answers with normosecretion of the glands, but this difference is not statistically significant (p > 0.1).
它在妊娠12至18周新生儿气管支气管系统的软肌肉组织中体外表达，伴有气管腺的分泌亢进和正常分泌。在对30例死于尸检的儿童气管标本进行研究时，观察了气管软肌肉组织（SMT）对浓度为1×10⁻⁴、1×10⁻³、1×10⁻²、1×10⁻¹M/L的乙酰胆碱、多巴胺、组胺和血清素的反应。结果表明，上述浓度的乙酰胆碱和组胺引发了气管腺分泌亢进和正常分泌情况下GMT的统计学显著反应（p < 0.01）。相反，多巴胺和血清素未引发这些结构的统计学显著反应（p > 0.1），这表明在这个年龄段，气管支气管系统中的多巴胺能和血清素能受体发育也不充分。气管腺分泌亢进的气管支气管环的反应比腺体正常分泌的反应略为明显，但这种差异无统计学意义（p > 0.1）。
