Li Qing, Whalen Christopher C, Albert Jeffrey M, Larkin Rhonda, Zukowski Lynn, Cave M Donald, Silver Richard F
Department of Medicine, Case Western Reserve University School of Medicine, and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA.
Infect Immun. 2002 Nov;70(11):6489-93. doi: 10.1128/IAI.70.11.6489-6493.2002.
Significant differences were observed in the capacities of Mycobacterium tuberculosis clinical isolates to grow within human monocytes. Genotyping indicated that the four most rapidly growing isolates were members of the Beijing strain family. M. tuberculosis strain H37Rv provided more reproducible infection than the clinical isolates or M. tuberculosis Erdman.
在结核分枝杆菌临床分离株在人单核细胞内生长的能力方面观察到显著差异。基因分型表明,四个生长最快的分离株是北京菌株家族的成员。结核分枝杆菌H37Rv菌株比临床分离株或结核分枝杆菌 Erdman 提供了更可重复的感染。