Casterline J L, Yip G
Arch Environ Contam Toxicol. 1975;3(3):319-29. doi: 10.1007/BF02220744.
Exposure to Cd and/or 109Cd has shown that the element was efficiently accumulated in oysters and soybeans as well as in rats. Differential centrifugation of oyster, soybean, rat liver, and rat kidney homogenates followed by analysis showed that Cd was associated primarily with proteins in the 105,000 X g supernatants. Separation of these proteins by Sephadex chromatography and subsequent analysis by atomic absorption spectroscopy or by radioactivity measurements revealed that Cd in oysters and rat organs was principally bound to proteins of 9,200 to 13,800 molecular weight. A significant amount of Cd in oysters was also associated with fractions of greater than 50,000 and less than 3,000 molecular weights. Almost all of the Cd in soybeans was found to be bound to molecules of greater than 50,000 molecular weight.
对镉（Cd）和/或109镉的暴露研究表明，该元素能在牡蛎、大豆以及大鼠体内有效蓄积。对牡蛎、大豆、大鼠肝脏和大鼠肾脏匀浆进行差速离心后分析发现，镉主要与105,000×g上清液中的蛋白质结合。通过葡聚糖凝胶色谱法分离这些蛋白质，随后用原子吸收光谱法或放射性测量法进行分析，结果显示，牡蛎和大鼠器官中的镉主要与分子量为9200至13800的蛋白质结合。牡蛎中大量的镉还与分子量大于50000和小于3000的组分相关。几乎所有大豆中的镉都与分子量大于50000的分子结合。
