伴侣蛋白走向成熟。
Chaperones come of age.
作者信息
Soti Csaba, Csermely Péter
机构信息
Department of Medical Chemistry, Semmelweis University, Budapest, Hungary.
出版信息
Cell Stress Chaperones. 2002 Apr;7(2):186-90. doi: 10.1379/1466-1268(2002)007<0186:ccoa>2.0.co;2.
Abstract
Chaperone function plays a key role in repairing proteotoxic damage, in the maintenance of cell architecture, and in cell survival. Here, we summarize our current knowledge about changes in chaperone expression and function in the aging process, as well as their involvement in longevity and cellular senescence.
摘要
伴侣蛋白功能在修复蛋白质毒性损伤、维持细胞结构和细胞存活方面发挥着关键作用。在此，我们总结了目前关于衰老过程中伴侣蛋白表达和功能变化的知识，以及它们在寿命和细胞衰老中的作用。
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