Hunt R C, Gold E, Brown J C
Biochim Biophys Acta. 1975 Dec 16;413(3):453-8. doi: 10.1016/0005-2736(75)90128-5.
The non-penetrating lactoperoxidase iodination probe has been employed in conjunction with synchronously dividing populations of mouse L cells to identify a high molecular weight protein is preferentially exposed on the L cell surface during G1 phase of the cell cycle. Progression of cells from G1 to S is accompanied by a marked decrease in tha availability of this structure, called band 1, to lactoperoxidase-catalyzed iodination and it remains unavailable until cells re-enter G1. It is suggested that the band 1 polypeptide may be functionally involved in the regulation of L cell growth.
非穿透性乳过氧化物酶碘化探针已与同步分裂的小鼠L细胞群体联合使用，以鉴定一种高分子量蛋白质，该蛋白质在细胞周期的G1期优先暴露于L细胞表面。细胞从G1期进入S期的过程中，这种称为带1的结构对乳过氧化物酶催化碘化的可用性显著降低，并且在细胞重新进入G1期之前一直保持不可用状态。有人提出，带1多肽可能在功能上参与L细胞生长的调节。
