Bettane M, Hermier B, Dubert J M, Paraf A
Biochimie. 1976;58(6):731-6. doi: 10.1016/s0300-9084(76)80398-7.
Lactoperoxidase catalyzed iodination of cell surface proteins has been used to compare theophylline and ouabain resistant variants with the drug sensitive parental cell lines. In cells showing contact inhibition a high molecular weight protein was observed to be preferentially labelled. In contrast this was not observed for non contact inhibited cells. These results support a previously suggested correlation between growth regulation and the exposure of this cell surface protein.
乳过氧化物酶催化的细胞表面蛋白碘化已被用于比较茶碱和哇巴因抗性变体与药物敏感的亲本细胞系。在表现出接触抑制的细胞中，观察到一种高分子量蛋白被优先标记。相比之下，在未表现出接触抑制的细胞中未观察到这种情况。这些结果支持了先前提出的生长调节与这种细胞表面蛋白暴露之间的相关性。
