Kieser Katharina E, Baskett Thomas F
Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, Nova Scotia, Canada.
Obstet Gynecol. 2002 Oct;100(4):749-53. doi: 10.1016/s0029-7844(02)02161-0.
To review the incidence, associated factors, methods of diagnosis, and maternal and perinatal morbidity and mortality associated with uterine rupture in one Canadian province.
Using a perinatal database, all cases of uterine rupture in the province of Nova Scotia for the 10-year period 1988-1997 were identified and the maternal and perinatal mortality and morbidity reviewed in detail.
Over the 10 years, there were 114,933 deliveries with 39 cases of uterine rupture: 18 complete and 21 incomplete (dehiscence). Thirty-six women had a previous cesarean delivery: 33 low transverse, two classic, one low vertical. Of the 114,933 deliveries, 11,585 (10%) were in women with a previous cesarean delivery. Uterine rupture in those undergoing a trial for vaginal delivery (4516) was complete rupture in 2.4 per 1000 and dehiscence in 2.4 per 1000. There were no maternal deaths, and maternal morbidity was low in patients with dehiscence. In comparison, 44% of those with complete uterine rupture received blood transfusion (odds ratio 7.60, 95% confidence interval 1.14, 82.14, P =.025). Two perinatal deaths were attributable to complete uterine rupture, one after previous cesarean delivery. Compared with dehiscence, infants born after uterine rupture had significantly lower 5-minute Apgar scores (P <.001) and asphyxia, needing ventilation for more than 1 minute (P <.01).
In 92% of cases, uterine rupture was associated with previous cesarean delivery. Uterine dehiscence was associated with minimal maternal and perinatal morbidity. In contrast, complete uterine rupture was associated with significantly more maternal blood transfusion and neonatal asphyxia.
回顾加拿大一个省份子宫破裂的发生率、相关因素、诊断方法以及孕产妇和围产期发病率及死亡率。
利用围产期数据库,确定1988年至1997年这10年间新斯科舍省所有子宫破裂病例,并详细回顾孕产妇和围产期的死亡率及发病率。
在这10年中,共有114,933例分娩,其中39例子宫破裂:18例完全破裂,21例不完全破裂(裂开)。36名女性曾行剖宫产:33例低位横切口,2例经典切口,1例低位纵切口。在114,933例分娩中,11,585例(10%)为有剖宫产史的女性。试产(4516例)中的子宫破裂完全破裂发生率为每1000例中有2.4例,裂开发生率为每1000例中有2.4例。无孕产妇死亡,裂开患者的孕产妇发病率较低。相比之下,完全子宫破裂患者中有44%接受了输血(优势比7.60,95%置信区间1.14, 82.14,P = 0.025)。两例围产期死亡归因于完全子宫破裂,其中1例发生在既往剖宫产术后。与裂开相比,子宫破裂后出生婴儿的5分钟阿氏评分显著更低(P < 0.001),且发生窒息,需要通气超过1分钟(P < 0.01)。
92%的病例中,子宫破裂与既往剖宫产有关。子宫裂开与孕产妇和围产期发病率极低相关。相比之下,完全子宫破裂与更多的孕产妇输血和新生儿窒息显著相关。