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与子宫破裂和裂开相关的风险因素:一项加拿大的横断面研究。

Risk Factors Associated with Uterine Rupture and Dehiscence: A Cross-Sectional Canadian Study.

机构信息

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.

Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.

出版信息

Rev Bras Ginecol Obstet. 2021 Nov;43(11):820-825. doi: 10.1055/s-0041-1739461. Epub 2021 Dec 6.

DOI:10.1055/s-0041-1739461
PMID:34872139
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10183935/
Abstract

OBJECTIVE

To compare maternal and perinatal risk factors associated with complete uterine rupture and uterine dehiscence.

METHODS

Cross-sectional study of patients with uterine rupture/dehiscence from January 1998 to December 2017 (30 years) admitted at the Labor and Delivery Unit of a tertiary teaching hospital in Canada.

RESULTS

There were 174 (0.1%) cases of uterine disruption (29 ruptures and 145 cases of dehiscence) out of 169,356 deliveries. There were associations between dehiscence and multiparity (odds ratio [OR]: 3.2;  = 0.02), elevated maternal body mass index (BMI; OR: 3.4;  = 0.02), attempt of vaginal birth after a cesarian section (OR: 2.9;  = 0.05) and 5-minute low Apgar score (OR: 5.9;  < 0.001). Uterine rupture was associated with preterm deliveries (36.5 ± 4.9 versus 38.2 ± 2.9;  = 0.006), postpartum hemorrhage (OR: 13.9;  < 0.001), hysterectomy (OR: 23.0;  = 0.002), and stillbirth (OR: 8.2;  < 0.001). There were no associations between uterine rupture and maternal age, gestational age, onset of labor, spontaneous or artificial rupture of membranes, use of oxytocin, type of uterine incision, and birthweight.

CONCLUSION

This large cohort demonstrated that there are different risk factors associated with either uterine rupture or dehiscence. Uterine rupture still represents a great threat to fetal-maternal health and, differently from the common belief, uterine dehiscence can also compromise perinatal outcomes.

摘要

目的

比较与完全性子宫破裂和子宫破裂相关的母体和围生期危险因素。

方法

对 1998 年 1 月至 2017 年 12 月(30 年)期间在加拿大一家三级教学医院分娩和分娩单位就诊的子宫破裂/破裂患者进行横断面研究。

结果

在 169356 例分娩中,有 174 例(0.1%)发生子宫破裂(29 例破裂和 145 例破裂)。子宫破裂与多胎妊娠(比值比[OR]:3.2;=0.02)、产妇体重指数(BMI)升高(OR:3.4;=0.02)、剖宫产术后阴道试产(OR:2.9;=0.05)和 5 分钟低 Apgar 评分(OR:5.9;<0.001)有关。子宫破裂与早产(36.5±4.9与 38.2±2.9;=0.006)、产后出血(OR:13.9;<0.001)、子宫切除术(OR:23.0;=0.002)和死胎(OR:8.2;<0.001)有关。子宫破裂与产妇年龄、胎龄、临产开始、自发性或人工破膜、催产素使用、子宫切口类型和出生体重无关。

结论

本大规模队列研究表明,与子宫破裂或破裂相关的危险因素不同。子宫破裂仍然对母婴健康构成巨大威胁,而且与普遍的看法不同,子宫破裂也会影响围产期结局。

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本文引用的文献

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Determinants of Uterine Rupture and Its Management Outcomes among Mothers Who Gave Birth at Public Hospitals of Tigrai, North Ethiopia: An Unmatched Case Control Study.埃塞俄比亚北部提格雷公立医院产妇子宫破裂的决定因素及其管理结果:一项非匹配病例对照研究
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Early Accreta and Uterine Rupture in the Second Trimester.孕中期的早期胎盘植入和子宫破裂
Cureus. 2018 Jul 1;10(7):e2904. doi: 10.7759/cureus.2904.
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Outcome of vaginal birth after cesarean section: A retrospective comparative analysis of spontaneous versus induced labor in women with one previous cesarean section.剖宫产术后阴道分娩的结局:对有一次剖宫产史的女性自然分娩与引产的回顾性比较分析。
Ann Afr Med. 2018 Jul-Sep;17(3):145-150. doi: 10.4103/aam.aam_54_17.
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Prior caesarean section and likelihood of vaginal birth, 2012-2016, China.2012-2016 年中国剖宫产史与阴道分娩可能性
Bull World Health Organ. 2018 Aug 1;96(8):548-557. doi: 10.2471/BLT.17.206433. Epub 2018 Jul 16.
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Maternal age potentiates the impact of operative birth on serious neonatal outcomes.产妇年龄会增强手术分娩对严重新生儿结局的影响。
J Matern Fetal Neonatal Med. 2020 Feb;33(4):598-605. doi: 10.1080/14767058.2018.1498478. Epub 2018 Sep 10.
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The International Network of Obstetric Survey Systems study of uterine rupture: a descriptive multi-country population-based study.国际产科调查系统网络对子宫破裂的研究:一项多国家基于人群的描述性研究。
BJOG. 2019 Feb;126(3):370-381. doi: 10.1111/1471-0528.15271. Epub 2018 Jun 12.
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