Fattore E, Fanelli R, La Vecchia C
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
J Epidemiol Community Health. 2002 Nov;56(11):831-2. doi: 10.1136/jech.56.11.831.
Persistent organic pollutants are a heterogeneous group of chemicals sharing a number a common properties, including long term persistence and diffusion in the environment, and bioaccumulation through the food chain. Animal experiments and epidemiological studies suggest that the most sensitive adverse effects, such as disturbances on metabolism, development, and reproductive system, may occur in the range of current human exposure. Although the potential cancer risk of persistent organic pollutants remains undefined, the implementation of actions to reduce the exposure to these substances, which mainly occurs through the diet, is important.
持久性有机污染物是一组性质各异的化学物质，它们具有许多共同特性，包括在环境中的长期持久性和扩散性，以及通过食物链的生物累积性。动物实验和流行病学研究表明，当前人类接触水平下可能会出现一些最敏感的不良反应，如对新陈代谢、发育和生殖系统的干扰。尽管持久性有机污染物的潜在癌症风险尚不明确，但采取行动减少主要通过饮食接触这些物质的情况非常重要。
