Levy Jean-Paul
Institut Pasteur, 28, rue du Docteur-Roux, 75724 Paris, France.
C R Biol. 2002 Aug;325(8):897-9; discussion 911-5. doi: 10.1016/s1631-0691(02)01504-4.
Prevention against the weapons of bioterrorists is limited by the multiplicity of agents that could be used. Against smallpox, stocks of the classical vaccine must be prepared, but this vaccine is dangerous and we must look for a new and safer vaccine. A vaccine against anthrax is probably possible relatively soon. One may be less optimistic concerning plague, since it is not sure that we could protect against the pulmonary plague, but research in this field is an emergency. The large number of viruses capable of inducing haemorrhagic fevers makes especially difficult the preparation of vaccines against these infections. We must also make available monoclonal antibodies that could be used as therapies against toxin, notably botulism, or against antibiotic-resistant bacteria.
对生物恐怖主义者所使用武器的防范因可能被利用的病原体种类繁多而受到限制。针对天花，必须储备传统疫苗，但这种疫苗具有危险性，我们必须寻找一种新的、更安全的疫苗。针对炭疽的疫苗可能相对较快就能研制出来。对于鼠疫，人们可能就没那么乐观了，因为我们不一定能预防肺鼠疫，但该领域的研究刻不容缓。大量能够引发出血热的病毒使得针对这些感染的疫苗研制格外困难。我们还必须提供可用于治疗毒素（尤其是肉毒中毒）或抗抗生素细菌的单克隆抗体。
