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利用人工智能和热成像图对乳腺癌进行计算机化检测。

Computerized detection of breast cancer with artificial intelligence and thermograms.

作者信息

Ng E Y-K, Fok S C, Peh Y C, Ng F C, Sim L S J

机构信息

College of Engineering, School of Mechanical and Production Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798.

出版信息

J Med Eng Technol. 2002 Jul-Aug;26(4):152-7. doi: 10.1080/03091900210146941.

Abstract

This paper shows the concurrent use of thermography and artificial neural networks (ANN) for the diagnosis of breast cancer, a disease that is growing in prominence in women all over the world. It has been reported that breast thermography itself could detect breast cancer up to 10 years earlier than the conventional golden methods such as mammography, in particular in the younger patient. However, the accuracy of thermography is dependent on many factors such as the symmetry of the breasts' temperature and temperature stability. A woman's body temperature is known to be stable in certain periods after menstruation and it was found that the accuracy of thermography in women whose thermal images are taken in a suitable period (5th - 12th and 21st day of menstruation) is higher (80%) than the total population of patients (73%). The stability of the body temperature will depend on physiological state. This paper examines the use of ANN to complement the infrared heat radiating from the surface of the body with other physiological data. Four backpropagation neural networks were developed and trained using the results from the Singapore General Hospital patients' physiological data and thermographs. Owing to the inaccuracies found in thermography and the low population size gathered for this project, the networks developed could only accurately diagnose about 61.54% of the breast cancer cases. Nevertheless, the basic neural network framework has been established and it has great potential for future development of an intelligent breast cancer diagnosis system. This would be especially useful to the teenagers and young adults who are unsuitable for mammography at a young age. An intelligent breast thermography-neural network will be able to give an accurate diagnosis of breast cancer and can make a positive impact on breast disease detection.

摘要

本文展示了热成像技术与人工神经网络(ANN)在乳腺癌诊断中的同时应用,乳腺癌在全球女性中日益凸显。据报道,乳腺热成像本身可在比传统黄金方法(如乳房X线摄影)早达10年时检测出乳腺癌,尤其在年轻患者中。然而,热成像的准确性取决于许多因素,如乳房温度的对称性和温度稳定性。已知女性体温在月经后的某些时期是稳定的,并且发现,在合适时期(月经第5 - 12天和第21天)拍摄热成像的女性中,热成像的准确性(80%)高于患者总体(73%)。体温的稳定性将取决于生理状态。本文研究了使用人工神经网络,将人体表面辐射的红外热与其他生理数据相结合。利用新加坡总医院患者的生理数据和热成像结果,开发并训练了四个反向传播神经网络。由于热成像中发现的不准确之处以及本项目收集的样本量较小,所开发的网络仅能准确诊断约61.54%的乳腺癌病例。尽管如此,基本的神经网络框架已经建立,并且在智能乳腺癌诊断系统的未来发展中具有巨大潜力。这对于年轻时不适合进行乳房X线摄影的青少年和年轻成年人尤其有用。智能乳腺热成像 - 神经网络将能够准确诊断乳腺癌,并对乳腺疾病检测产生积极影响。

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