重复DNA、基因组系统结构与基因组重组

Repetitive DNA, genome system architecture and genome reorganization.

作者信息

Shapiro James A

机构信息

Department of Biochemistry and Molecular Biology, University of Chicago, IL 60637, USA.

出版信息

Res Microbiol. 2002 Sep;153(7):447-53. doi: 10.1016/s0923-2508(02)01344-x.

DOI:10.1016/s0923-2508(02)01344-x

PMID:12405352

Abstract

Repetitive DNA elements are major organizational components of the genome involved in replication, in transmission to daughter cells, and controlling expression of genomic coding sequences. Repetitive elements format the genome system architecture characteristic of each taxonomic group. Appreciating the functional significance of repetitive DNA provides new concepts of genome organization and genome reorganization in evolution.

摘要

重复DNA元件是基因组的主要组织成分，参与复制、向子细胞的传递以及基因组编码序列表达的控制。重复元件形成了每个分类群特有的基因组系统结构。认识到重复DNA的功能意义为进化中的基因组组织和基因组重组提供了新的概念。