Brin V B
Biull Eksp Biol Med. 1975 Nov;80(11):14-7.
Experiments were conducted on dogs aged 18-22 days, 2-3 month-old and adult dogs. Arterial blood pressure, cardiac output, heart rate and total peripheral resistance during the infusion of synthetic angiotensin-II-amide in a dose of 2 mug/kg per minute were studied. An increase of arterial pressure in adult dogs during the action of angiotensin-II was connected with the elevation of the total peripheral resistance. An increase of the total peripheral resistance and also of the cardiac output was seen in the puppies. The differences in the degree of increase of the arterial blood pressure in adult dogs and puppies were not marked.
对18 - 22日龄的幼犬、2 - 3月龄的幼犬和成年犬进行了实验。研究了以每分钟2微克/千克的剂量输注合成血管紧张素 - II - 酰胺期间的动脉血压、心输出量、心率和总外周阻力。成年犬在血管紧张素 - II作用期间动脉压升高与总外周阻力升高有关。幼犬则出现总外周阻力和心输出量增加。成年犬和幼犬动脉血压升高程度的差异并不明显。
