Onodera Masakazu, Mori Masahiro, Koga Michiaki, Kamitsukasa Ikuo, Fukutake Toshio, Hattori Takamichi, Yuki Nobuhiro, Kuwabara Satoshi
Department of Neurology, Chiba Rosai Hospital, Chiba, Japan.
J Neurol Sci. 2002 Dec 15;205(1):83-4. doi: 10.1016/s0022-510x(02)00241-1.
We describe a patient with acute isolated bulbar palsy following enteritis. A 29-year-old man developed dysphagia and nasal voice without limb weakness, ataxia, or areflexia. High titres of serum anti-GT1a and anti-Campylobacter jejuni IgG antibodies were detected. He was treated with plasmapheresis, resulting in rapid clinical improvement. This case suggests that an acute isolated bulbar palsy may be caused by a pathology relating to Guillain-Barré syndrome (GBS), in which anti-GT1a IgG antibody may have a role.
我们描述了一名患肠炎后出现急性孤立性延髓麻痹的患者。一名29岁男性出现吞咽困难和鼻音，无肢体无力、共济失调或反射消失。检测到高滴度的血清抗GT1a和抗空肠弯曲菌IgG抗体。他接受了血浆置换治疗，临床症状迅速改善。该病例表明，急性孤立性延髓麻痹可能由与吉兰-巴雷综合征（GBS）相关的病理引起，其中抗GT1a IgG抗体可能起作用。
