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轻度或中度子宫内膜异位症不孕女性的生育力:一项临床研究

Fecundity of infertile women with minimal or mild endometriosis. A clinical study.

作者信息

Milingos S, Mavrommatis C, Elsheikh A, Kallipolitis G, Loutradis D, Diakomanolis E, Michalas S

机构信息

Division of Fertility - Sterility, 1st Department of Obstetrics and Gynecology, University of Athens, Alexandra University Hospital, Athens, 1 A, Pindarou street, 14578 Ekali, Greece.

出版信息

Arch Gynecol Obstet. 2002 Nov;267(1):37-40. doi: 10.1007/s00404-001-0262-7.

DOI:10.1007/s00404-001-0262-7
PMID:12410372
Abstract

Despite significant developments in medical and surgical approaches for treating endometriosis, the optimal therapy has yet to be established. The relationship between prevalence of fecundity and stage of endometriosis according to their management was studied. Of 151 consecutive women with laparoscopy-proved endometriosis stage-1 and 2, operative laparoscopy was performed in 49, medical treatment in 59 and expectant management in 43 cases. During a 24-month period the cumulative pregnancy rates were found to be 36.7%, 30.5% and 20.9% respectively. Survival analysis showed that the probability of carrying the pregnancy beyond 20 weeks were 30.6%, 25.4% and 16.2% respectively. Diagnosis and treatment of early endometriosis is beneficial for the infertile women. Laparoscopic surgery seems to be the milestone of treatment in these cases, increasing the fecundity and involving minimal risk.

摘要

尽管在子宫内膜异位症的医学和外科治疗方法上取得了重大进展,但最佳治疗方案尚未确立。根据治疗方式,研究了生育力患病率与子宫内膜异位症分期之间的关系。在151例经腹腔镜证实为1期和2期子宫内膜异位症的连续女性患者中,49例行手术腹腔镜检查,59例接受药物治疗,43例采用期待治疗。在24个月期间,累积妊娠率分别为36.7%、30.5%和20.9%。生存分析表明,妊娠超过20周的概率分别为30.6%、25.4%和16.2%。早期子宫内膜异位症的诊断和治疗对不孕女性有益。腹腔镜手术似乎是这些病例治疗的里程碑,可提高生育力且风险最小。

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引用本文的文献

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The Impact of Laparoscopic Surgery on Fertility Outcomes in Patients with Minimal/Mild Endometriosis.腹腔镜手术对轻度/中度子宫内膜异位症患者生育结局的影响。
J Clin Med. 2024 Aug 15;13(16):4817. doi: 10.3390/jcm13164817.
2
Combination of noninvasive methods in diagnosis of infertile women with minimal or mild endometriosis, a retrospective study in China.非侵入性方法联合诊断轻度或轻微子宫内膜异位症的不孕女性:一项中国的回顾性研究
Medicine (Baltimore). 2019 Aug;98(31):e16695. doi: 10.1097/MD.0000000000016695.
3
The Role of GnRH Analogues in Improving Outcome in Women Undergoing Superovulation and Intrauterine Insemination after Surgical Correction of Mild Endometriosis: A Randomized Controlled Trial.
GnRH类似物在轻度子宫内膜异位症手术矫正后接受超排卵和宫内人工授精的女性中改善结局的作用:一项随机对照试验
Eurasian J Med. 2018 Jun;50(2):105-110. doi: 10.5152/eurasianjmed.2018.17379. Epub 2018 Jun 1.
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In vitro fertilization outcome in women with endometriosis & previous ovarian surgery.子宫内膜异位症及既往卵巢手术女性的体外受精结局
Indian J Med Res. 2014 Sep;140(3):387-91.