Pari L, Venkateswaran S
Department of Biochemistry, Annamalai University, Annamalai Nagar - 608 002, Tamil Nadu, India.
Phytother Res. 2002 Nov;16(7):662-4. doi: 10.1002/ptr.1036.
Scoparia dulcis L. commonly known as 'Sweet Broomweed' is widely used in Indian folk medicine for the treatment of diabetes mellitus. Oral administration of 0.15, 0.30 and 0.45 g/kg body weight of the aqueous extract of the Scoparia dulcis leaves (SLEt) for 45 days resulted in a significant reduction in blood glucose, glycosylated haemoglobin and an increase in total haemoglobin but in the case of 0.45 g/kg body weight the effect was highly significant. The aqueous extract also prevented a decrease in the body weight. An oral glucose tolerance test was also performed in experimental diabetic rats, in which there was a significant improvement in glucose tolerance in animals treated with SLEt and the effect was comparable to that of glibenclamide.
甜扫帚草（Scoparia dulcis L.）俗称“甜帚菊”，在印度民间医学中广泛用于治疗糖尿病。以0.15、0.30和0.45克/千克体重的剂量口服甜扫帚草叶水提取物（SLEt）45天，可显著降低血糖、糖化血红蛋白，并增加总血红蛋白，但0.45克/千克体重剂量的效果极为显著。该水提取物还可防止体重下降。对实验性糖尿病大鼠进行了口服葡萄糖耐量试验，结果显示，用SLEt治疗的动物的葡萄糖耐量有显著改善，其效果与格列本脲相当。
