Saludes Jonel P, Garson Mary J, Franzblau Scott G, Aguinaldo Alicia M
Research Center for the Natural Sciences, University of Santo Tomas, Espana, Manila 1008, Philippines.
Phytother Res. 2002 Nov;16(7):683-5. doi: 10.1002/ptr.1003.
A crude ethanol extract and hexane fraction from Morinda citrifolia Linn. (Rubiaceae) show antitubercular activity. The major constituents of the hexane fraction are E-phytol, cycloartenol, stigmasterol, beta-sitosterol, campesta-5,7,22-trien-3beta-ol and the ketosteroids stigmasta-4-en-3-one and stigmasta-4-22-dien-3-one. E-Phytol, a mixture of the two ketosteroids, and the epidioxysterol derived from campesta-5,7,22-trien-3beta-ol all show pronounced antitubercular activity.
来自巴戟天(茜草科)的粗乙醇提取物和正己烷馏分显示出抗结核活性。正己烷馏分的主要成分是叶绿醇、环阿屯醇、豆甾醇、β-谷甾醇、campesta-5,7,22-三烯-3β-醇以及甾酮类化合物豆甾-4-烯-3-酮和豆甾-4,22-二烯-3-酮。叶绿醇、两种甾酮类化合物的混合物以及源自campesta-5,7,22-三烯-3β-醇的表二氧甾醇均显示出显著的抗结核活性。