Mukherjee Kakali, Saha B P, Mukherjee Pulok K
Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta - 700032, India.
Phytother Res. 2002 Nov;16(7):696-9. doi: 10.1002/ptr.1017.
Methanol extract of Leucas lavandulaefolia (LLFE) was evaluated for different psychopharmacological profiles with various animal models in rats and mice. The extract showed a potential reduction in spontaneous activity and caused a significant decrease in exploratory behavioural pattern by the head dip and Y-maze test. It also showed a significant reduction in muscle relaxant activity by rotarod, 30 degrees inclined screen and traction tests. The extract showed a remarkable potentiation of pentobarbitone induced sleeping time in mice.
对薰衣草叶绣球(LLFE)的甲醇提取物在大鼠和小鼠的多种动物模型上进行了不同精神药理学特征的评估。该提取物显示出能潜在降低自发活动,并通过头部浸入和Y迷宫试验使探索行为模式显著减少。通过转棒试验、30度倾斜筛板试验和牵引试验,它还显示出肌肉松弛活性显著降低。该提取物使小鼠中戊巴比妥诱导的睡眠时间显著延长。