48例视网膜血管瘤的临床特征

[Clinical features of 48 cases with retinal angioma].

作者信息

Peng Xiaoyan, Wang Guanglu, Zhang Feng, Meng Shumin, Lu Ning

机构信息

Beijing Tong Ren Ophthalmic Center, Capital University of Medical Sciences, Beijing 100730, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2002 Sep;38(9):550-2.

PMID:12410976

Abstract

OBJECTIVE

To summarize the clinical features of 48 cases with retinal angioma.

METHODS

The 48 cases were retrospectively summarized. The clinical features included sex distribution, age at first visit, chief complains, visual acuity, and the size, number and site of retinal angioma identified by fundus fluorescein angiography (FFA) and fundus examination.

RESULTS

There were 24 males and 24 females. The mean age at onset was 27 years. Thirteen cases (27%) had bilateral retinal angiomas. Multiple angiomas were found in 22 eyes (36%). Seventeen cases (35%) were identified as von Hippel Lindau (VHL) disease. The location of angioma was in the temporal retina in all the cases with only one angioma. All the symptomatic tumors were larger than 1 disc diameter (DD). The common symptoms of patients with retinal angioma were visual loss in 77% cases, floaters in 15% cases and distortion in 8% cases.

CONCLUSION

Retinal angioma is an uncommon disease prone to be involved in both eyes and to primarily damage the vision of young and middle-aged adults.

摘要

目的

总结48例视网膜血管瘤患者的临床特征。

方法

对48例患者进行回顾性总结。临床特征包括性别分布、初诊年龄、主要症状、视力，以及通过眼底荧光血管造影（FFA）和眼底检查确定的视网膜血管瘤的大小、数量和部位。

结果

男性24例，女性24例。平均发病年龄为27岁。13例（27%）有双侧视网膜血管瘤。22只眼（36%）发现有多发性血管瘤。17例（35%）被诊断为冯·希佩尔-林道（VHL）病。所有单发血管瘤病例的血管瘤均位于颞侧视网膜。所有有症状的肿瘤均大于1个视盘直径（DD）。视网膜血管瘤患者的常见症状为视力丧失（77%）、飞蚊症（15%）和视物变形（8%）。