注意缺陷多动障碍儿童的品行问题、性别与成人期精神科结局
Conduct problems, gender and adult psychiatric outcome of children with attention-deficit hyperactivity disorder.
作者信息
Dalsgaard Søren, Mortensen Preben Bo, Frydenberg Morten, Thomsen Per Hove
机构信息
Psychiatric Hospital for Children and Adolescents, Aarhus University Hospital, Denmark.
出版信息
Br J Psychiatry. 2002 Nov;181:416-21. doi: 10.1192/bjp.181.5.416.
BACKGROUND
Attention-deficit hyperactivity disorder (ADHD) is a common childhood condition, and is more prevalent in boys. The adult outcome of girls with ADHD has never been studied.
AIMS
To identify predictors for adult psychiatric outcome of children with ADHD, including gender and comorbidity.
METHOD
Children aged 4-15 years, referred for hyperactivity/inattention and treated with stimulants were included (n=208). The Psychiatric Case Register provided follow-up data on psychiatric admissions in adulthood until a mean age of 31 years.
RESULTS
A total of 47 cases (22.6%) had a psychiatric admission in adulthood. Conduct problems in childhood were predictive (hazard ratio HR=2.3; 95% CI 1.22-4.33). Girls had a higher risk compared with boys (HR=2.4; 95% CI 1.1-5.6).
CONCLUSIONS
Girls with ADHD had a higher risk of adult psychiatric admission than boys. Conduct problems were also associated with a higher risk. Girls with ADHD with conduct problems had a very high risk of a psychiatric admission in adulthood.
背景
注意力缺陷多动障碍（ADHD）是一种常见的儿童疾病，在男孩中更为普遍。患有ADHD的女孩的成人期结局从未被研究过。
目的
确定患有ADHD的儿童成人期精神科结局的预测因素，包括性别和共病情况。
方法
纳入年龄在4至15岁、因多动/注意力不集中前来就诊并接受兴奋剂治疗的儿童（n = 208）。精神病病例登记册提供了成年期精神病住院的随访数据，直至平均年龄31岁。
结果
共有47例（22.6%）在成年期有精神病住院记录。儿童期的品行问题具有预测性（风险比HR = 2.3；95%置信区间1.22 - 4.33）。与男孩相比，女孩的风险更高（HR = 2.4；95%置信区间1.1 - 5.6）。
结论
患有ADHD的女孩成年期精神病住院的风险高于男孩。品行问题也与更高的风险相关。患有ADHD且有品行问题的女孩成年期精神病住院的风险非常高。
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