Kato Nobuya, Nakanishi Kazuhiro, Yoshino Shinichi, Ogawa Ryo
Department of Anesthesiology, Nippon Medical School, Tokyo, Japan.
Anesthesiology. 2002 Nov;97(5):1123-8. doi: 10.1097/00000542-200211000-00014.
In patients undergoing total knee arthroplasty, intraoperative pulmonary embolic events are rare, and most occur following tourniquet deflation. This embolization can be observed using transesophageal echocardiography. However, the authors have encountered sudden decreases in arterial oxygen partial pressure while a tourniquet is still inflated. Therefore, the current investigation was designed to detect emboli during the tourniquet inflation phase and to identify the composition of the echogenic material.
Forty-six patients were randomly assigned to undergo total knee arthroplasty without (control, n = 24) or with a tourniquet (n = 22). Hemodynamic monitoring, blood gas analysis, and continuous transesophageal echocardiography were performed during the total knee arthroplasty procedure. Right jugular blood specimens were collected whenever echogenic material was seen in the atrium.
In the tourniquet group, embolic events occurred in 27% of patients during femoral reaming and in 100% after tourniquet deflation. In the control group, emboli were detected in 54% of patients during femoral reaming. Most of the patients exhibited cardiopulmonary impairment after severe echogenic embolism, even while the tourniquet was inflated (two patients). None of the blood samples aspirated from the central catheters contained detectable material.
This prospective study showed that embolic events occurred during total knee arthroplasty, even while a tourniquet was inflated. An inflated tourniquet does not completely prevent pulmonary emboli.
在接受全膝关节置换术的患者中,术中肺栓塞事件很少见,且大多数发生在止血带放气后。这种栓塞可通过经食管超声心动图观察到。然而,作者遇到过在止血带仍处于充气状态时动脉血氧分压突然下降的情况。因此,本研究旨在检测止血带充气阶段的栓子,并确定回声物质的成分。
46例患者被随机分配接受全膝关节置换术,其中24例不使用止血带(对照组),22例使用止血带。在全膝关节置换手术过程中进行血流动力学监测、血气分析和连续经食管超声心动图检查。每当在心房中看到回声物质时,采集右颈静脉血标本。
在止血带组中,27%的患者在股骨扩髓时发生栓塞事件,100%的患者在止血带放气后发生栓塞事件。在对照组中,54%的患者在股骨扩髓时检测到栓子。大多数患者在发生严重的回声性栓塞后出现心肺功能损害,即使在止血带充气时也是如此(2例患者)。从中心静脉导管抽取的血液样本中均未检测到可检测物质。
这项前瞻性研究表明,全膝关节置换术期间即使止血带处于充气状态也会发生栓塞事件。充气止血带并不能完全预防肺栓塞。