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[放射性视网膜病变]

[Radiation-induced retinopathy].

作者信息

Lumbroso L, Dendale R, Fourquet A, Desjardins L

机构信息

Service d'ophtalmologie, Institut Curie, 26, rue d'Ulm, 75248, Paris, France.

出版信息

Cancer Radiother. 2002 Sep;6(5):289-95. doi: 10.1016/s1278-3218(02)00204-4.

Abstract

Radiation retinopathy is a retinal microangiopathy, observed after irradiation of the eye. It can rarely lead to neovascular glaucoma and enucleation due to pain. It is due to a progressive retinal capillary then vascular occlusion. Total irradiation dose, dose fraction, and surface of the irradiated retina seem to be strong predictive factors for radiation retinopathy. Patients who underwent an irradiation near the eye (skull base tumors, nasal and paranasal tumors, or brain tumors) should be followed by periodic ophthalmologic examination to detect and treat when necessary the non perfusion areas.

摘要

放射性视网膜病变是一种视网膜微血管病变,在眼部接受照射后出现。它很少会因疼痛导致新生血管性青光眼和眼球摘除。其病因是视网膜毛细血管进而血管逐渐闭塞。总照射剂量、剂量分割以及受照射视网膜的面积似乎是放射性视网膜病变的重要预测因素。眼部附近接受过照射的患者(如颅底肿瘤、鼻腔和鼻旁窦肿瘤或脑肿瘤患者)应定期接受眼科检查,以便在必要时检测和治疗无灌注区域。

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