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[胃溃疡、应激与精神分裂症。男性精神分裂症患者胃溃疡的发病率(作者译)]

[Gastric ulcers, stress and schizophrenia. Incidence of gastric ulcers in male schizophrenic patients (author's transl)].

作者信息

Hinterhuber H, Lochenegg L

出版信息

Arch Psychiatr Nervenkr (1970). 1975 Dec 22;220(4):335-45. doi: 10.1007/BF00342063.

Abstract

According to the hypothesis of a biochemical disorder, we found that schizophrenic patients show a modified reaction to stress. We have checked 668 male schizophrenic patients and found 18 ulcers (2.69%) this is contrasted by the average incidence of ulcers at the rate of 10%.12 of the 18 probands had preliminary serious somatic lesions. We came to the conslusion that the hypothalamic stress response is altered: Schizophrenic patients and the normal population show a significant difference to the incidence of gastric ulcers.

摘要

根据生化紊乱假说,我们发现精神分裂症患者对应激的反应有所改变。我们检查了668名男性精神分裂症患者,发现18例溃疡(2.69%),而溃疡的平均发病率为10%。这18名先证者中有12人有初步的严重躯体病变。我们得出结论,下丘脑应激反应发生了改变:精神分裂症患者与正常人群在胃溃疡发病率上存在显著差异。

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