Schumpelick V, Farthmann E
Arzneimittelforschung. 1976;26(3):386-8.
The protective effect of vitamin A on "restraint stress" ulcer formation was studied in rats. Animals receiving i.m. injections of 1000 or 2000 IU vitamin A, respectively, every 6 h after 19 h of immobilisation had significantly fewer and smaller ulcers than had the controls. There was no difference between the 2 doses. Only a few rats had no gastric ulcers at all, that means the protection was not absolute. Therapeutic use of vitamin A in the prophylaxis of stress ulcer is discussed.
研究了维生素A对大鼠“束缚应激”性溃疡形成的保护作用。在固定19小时后，分别每6小时接受1000或2000国际单位维生素A肌肉注射的动物，其溃疡数量明显少于对照组，且溃疡也更小。两种剂量之间没有差异。只有少数大鼠完全没有胃溃疡，这意味着这种保护并非绝对的。文中讨论了维生素A在预防应激性溃疡方面的治疗用途。
