Jiménez A, López-Trascasa M, Fontán G
Servicio de Immunologia, Hospital La Paz, Madrid, Spain.
Clin Exp Immunol. 1989 Nov;78(2):149-52.
IgG2 deficiency has been recently associated with the appearance of vasculitis. None of the 42 patients with IgG2 deficiency whom we studied has a history of vasculitis. We have also studied 56 patients with vasculitis, and found four of them with IgG2 levels below the normal range for their age. As a group, the vasculitis patients did not differ in the incidence of low IgG2 levels from a normal population. Three of the four vasculitis patients with low IgG2 levels had a Henoch-Schonlein syndrome, and the association between both features was statistically significant.
IgG2缺乏症最近被认为与血管炎的出现有关。我们研究的42例IgG2缺乏症患者均无血管炎病史。我们还研究了56例血管炎患者，发现其中4例IgG2水平低于其年龄的正常范围。总体而言，血管炎患者低IgG2水平的发生率与正常人群没有差异。4例IgG2水平低的血管炎患者中有3例患有过敏性紫癜综合征，这两种特征之间的关联具有统计学意义。
