Frost Megan C, Meyerhoff Mark E
Department of Chemistry, The University of Michigan, Ann Arbor 48109-1055, USA.
Curr Opin Chem Biol. 2002 Oct;6(5):633-41. doi: 10.1016/s1367-5931(02)00371-x.
Recently, progress has been made in the development of implantable chemical sensors capable of real-time monitoring of clinically important species such as PO(2), PCO(2), pH, glucose and lactate. The need for developing truly biocompatible materials for sensor fabrication remains the most significant challenge for achieving robust and reliable sensors capable of monitoring the real-time physiological status of patients.
最近，能够实时监测临床重要指标（如氧分压、二氧化碳分压、pH值、葡萄糖和乳酸）的可植入化学传感器的研发取得了进展。开发用于传感器制造的真正生物相容性材料的需求，仍然是实现能够监测患者实时生理状态的强大且可靠传感器的最大挑战。
