Treatment of vaginal agglutination associated with chronic graft-versus-host disease.

OBJECTIVE

To describe the presentation and clinical course of two patients after development of vaginal agglutination associated with chronic graft-versus-host disease.

DESIGN

Case report.

SETTING

Tertiary referral center for pelvic reconstructive surgery.

PATIENT(S): Two patients with the diagnosis of chronic graft-versus-host disease who later developed vaginal agglutination requiring treatment.

INTERVENTION(S): Surgical lysis of vaginal adhesions and postoperative use of vaginal dilators.

MAIN OUTCOME MEASURE(S): Successful treatment of vaginal adhesions.

RESULT(S): Both patients underwent successful surgical lysis of vaginal adhesions and maintained vaginal patency with postoperative use of vaginal dilators.

CONCLUSION(S): Prompt diagnosis of vaginal agglutination in patients with chronic graft-versus-host disease and appropriate surgical correction of this complication rather than prophylaxis is the correct treatment course.