Banka R, Ward M J
Department of Respiratory Medicine, Sherwood Forest Hospitals NHS Trust, King's Mill Hospital, Sutton in Ashfield, Nottinghamshire NG17 4JL, UK.
Postgrad Med J. 2002 Oct;78(924):621-2. doi: 10.1136/pmj.78.924.621.
Bronchiolitis obliterans and organising pneumonia (BOOP) presents with fever, dyspnoea, and other features that may be mistaken for pneumonia. Treatment is, however, very different, requiring corticosteroids. A man was admitted as an emergency with fever, dyspnoea, and non-productive cough. The chest radiograph showed consolidation which, despite antibiotics, progressed to become bilateral. BOOP was considered, and confirmed by transbronchial biopsy. The response to oral prednisolone was rapid with complete resolution of symptoms and radiographic consolidation within three weeks. The cause of BOOP is often never found; it is believed, however, that in this instance it occurred as a result of carbamazepine therapy started seven weeks earlier.
闭塞性细支气管炎伴机化性肺炎（BOOP）表现为发热、呼吸困难及其他可能被误诊为肺炎的症状。然而，其治疗方法却大不相同，需要使用皮质类固醇。一名男子因发热、呼吸困难和干咳作为急诊入院。胸部X光片显示有实变，尽管使用了抗生素，实变仍进展至双侧。考虑为BOOP，并经支气管活检确诊。口服泼尼松龙后反应迅速，症状在三周内完全缓解，影像学上的实变也消失。BOOP的病因常常难以查明；不过，据信在本例中，BOOP是七周前开始的卡马西平治疗所致。
