Cordier Jean-François
Department of Respiratory Medicine and Center for Orphan Lung Diseases, Louis Pradel Hospital, Claude Bernard University, 28 Avenue Doyen Lépine, 69677 Lyon (Bron), France.
Clin Chest Med. 2004 Dec;25(4):727-38, vi-vii. doi: 10.1016/j.ccm.2004.06.003.
Cryptogenic organizing pneumonia is a rare, distinct disorder that is sufficiently different from the other diseases in the group of idiopathic interstitial pneumonias to be designated as a separate entity. In its most typical presentation, it is characterized by dyspnea and cough, with multiple patchy alveolar opacities on pulmonary imaging. Definite diagnosis is obtained by the finding of buds of granulation tissue in the distal airspaces at lung biopsy. No cause (as infection, drug reaction, or associated disease as connective tissue disease) is found. Corticosteroid treatment is rapidly effective, but relapses are common on reducing or stopping treatment.
隐源性机化性肺炎是一种罕见的、独特的疾病，与特发性间质性肺炎组中的其他疾病有足够的差异，因此被指定为一个单独的实体。在其最典型的表现中，其特征为呼吸困难和咳嗽，肺部影像学显示有多个斑片状肺泡实变。通过肺活检在远端气腔中发现肉芽组织芽来明确诊断。未发现病因（如感染、药物反应或结缔组织病等相关疾病）。皮质类固醇治疗迅速有效，但在减少或停止治疗时复发很常见。
