Miller Lisa, Weissman Myrna
Clinical Psychology Program, Teachers College, Columbia University, New York, NY 10032, USA.
Depress Anxiety. 2002;16(3):114-7. doi: 10.1002/da.10047.
Rates of recurrent depression peak among women in their childbearing years, yet a large number of these women are not treated or do not seek maintenance treatment between episodes. Barriers to treatment include time constraints, demands of child care, and finances. A method for improving access to treatment of depression may be delivery of psychotherapy over the telephone. A 12-week pilot controlled clinical trial with random assignment was conducted to test the feasibility and efficacy of Interpersonal Psychotherapy delivered over the telephone (IPT-T) for depression in women (N=15 IPT-T and N=15 no treatment) with a life-time history of recurrent depression and low rates of previous treatment. Patients were interviewed at baseline and at 12 weeks by a blind and independent clinical evaluator to assess their symptom level and social functioning. IPT-T as compared to no treatment was significantly better in lowering symptoms of depression as measured by the Hamilton Rating Scale for Depression (p<.02), improving global functioning (GAS) (p<.02), and improving work and social functioning (p<.03-.05, respectively). These preliminary findings support the feasibility and helpfulness of IPT-T in preventing an increase in depressive symptoms among women with recurrent depression but current mild to moderately levels of depression.
复发性抑郁症的发病率在育龄女性中达到峰值，但其中大量女性在发作期间未接受治疗或未寻求维持治疗。治疗障碍包括时间限制、育儿需求和经济状况。一种改善抑郁症治疗可及性的方法可能是通过电话提供心理治疗。开展了一项为期12周的随机分组试点对照临床试验，以测试电话人际心理治疗（IPT-T）对有复发性抑郁症病史且既往治疗率低的女性抑郁症患者（IPT-T组15例，未治疗组15例）的可行性和疗效。在基线期和第12周时，由一位盲法且独立的临床评估员对患者进行访谈，以评估其症状水平和社会功能。与未治疗相比，IPT-T在降低汉密尔顿抑郁量表测量的抑郁症状（p<0.02）、改善整体功能（GAS）（p<0.02）以及改善工作和社会功能（分别为p<0.03 - 0.05）方面显著更好。这些初步研究结果支持了IPT-T在预防有复发性抑郁症但目前处于轻度至中度抑郁水平的女性抑郁症状加重方面的可行性和有效性。
