Larregue M, Babin P, Gallet P, Rat J P, Payen J
Med Cutan Ibero Lat Am. 1975;3(5):371-5.
On the stump of amputated limbs, a peculiar hyperkeratotic chronic lesion may be observed. The histological picture of this lesion shows a hyperkeratotic plug perforating the epidermis. In the dermis disorganised keratine lamelles are found. This lesion could be differenciated from Kyrle's disease by the fact that it consists of a single lesion of traumatic origin and by the presence of hypertrophic bundles underlying the hyperkeratosis.
在截肢肢体的残端，可观察到一种特殊的角化过度慢性病变。该病变的组织学表现为一个穿透表皮的角化过度栓子。在真皮层发现了紊乱的角蛋白薄片。这种病变可与凯尔氏病相鉴别，因为它由单个创伤性起源的病变组成，且在角化过度下方存在肥厚束。
